Abstract
Biology education is not culturally neutral; rather, it is deeply influenced by learners' cultural backgrounds, beliefs, values, and indigenous knowledge systems. This seminar critically examines how cultural context shapes the teaching and learning of Biology, particularly in multicultural and developing societies where diverse worldviews intersect with formal scientific knowledge. It explores the interaction between scientific knowledge and indigenous knowledge systems, learners' epistemological beliefs, language of instruction, and classroom practices, emphasizing how these factors influence students' understanding of biological concepts. The review highlights that culturally familiar examples, local environmental knowledge, and community-based experiences can significantly enhance learning outcomes. Findings reveal that when cultural contexts are effectively integrated into Biology education, learners demonstrate improved conceptual understanding, higher engagement, better retention, and increased relevance of scientific knowledge to real-life situations. Conversely, when cultural perspectives are ignored, learners may develop misconceptions, experience cognitive conflict, and become disengaged from the learning process. The seminar concludes that culturally responsive Biology teaching is essential for meaningful and inclusive science education. It recommends curriculum adaptation, continuous teacher training, and the deliberate integration of indigenous knowledge systems to bridge the gap between traditional understanding and modern scientific perspectives.

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